Compounded in U.S. 503A / 503B pharmaciesThird-party tested — potency, sterility, endotoxinPrescribed only by licensed U.S. providersCold-chain packed · tracked shippingCertificate of Analysis on every lotNo research-use chemicals — prescription onlyCompounded in U.S. 503A / 503B pharmaciesThird-party tested — potency, sterility, endotoxinPrescribed only by licensed U.S. providersCold-chain packed · tracked shippingCertificate of Analysis on every lotNo research-use chemicals — prescription only

Melanotan II

Commonly chosen for: Tanning, appetite, libido

Melanotan II shown as a sealed single-dose glass vial with a silver crimp cap
Representative product image. Packaging is determined by the dispensing pharmacy and may differ.

What it is

Melanotan II tells your skin to produce more melanin, so you tan with less sun exposure. It also acts on receptors involved in appetite and libido — PT-141 was developed out of that side of its activity. It carries real safety considerations: nausea, blood pressure changes, and the need to have existing moles checked by a dermatologist. Physician supervision genuinely matters with this one.

How it works

Melanotan II acts on melanocortin receptors, telling the pigment cells in your skin to produce more melanin — so you tan with less sun exposure.

The same receptor family is involved in appetite and libido, which is why those effects are also reported. PT-141 was developed out of that side of its activity.

It carries real safety considerations, which is why physician supervision genuinely matters with this one.

Who it's typically for

  • People seeking tanning support who accept close supervision.
  • People who have had their moles checked by a dermatologist.
  • People with no history of skin cancer or atypical moles.

What to know before starting

Read this part properly

Common side effects

Nausea and flushing are common, especially early. Darkening of existing moles and freckles, appetite changes, spontaneous erections and blood pressure changes are all reported.

Who should avoid it

Not appropriate with a history of melanoma or skin cancer, atypical or numerous moles, uncontrolled high blood pressure, or in pregnancy or breastfeeding. A dermatologist should check existing moles before and during use, and this does not replace sun protection.

Consult requirement

A video consult with a licensed provider is required.

This page is educational and is not medical advice. Nothing here is intended to diagnose, treat, cure or prevent any disease. Where you see the FDA-Approved Ingredient mark, the active ingredient is FDA-approved in at least one prescription medication. Products without it are prescribed based on your provider's clinical judgment and current research. Compounded preparations are not FDA-approved products in either case.

Often paired with

Questions people ask

More in Sexual Health & Hormones

View the category

PT-141

FDA-Approved Ingredient

Libido and sexual desire

Learn more

Kisspeptin

Natural hormone support, libido, fertility

Learn more

Oxytocin

FDA-Approved Ingredient

Intimacy, mood, connection

Learn more

Related reading

Ready to begin?

Start through the secure consultation workflow when the intake link becomes active.

Treatment is only available if determined medically appropriate by a licensed provider.

Find My PeptideShop →